An EU Horizon 2020 IMCUSTOMEYE project landmark paper has just been published in Biomedical Optics Express. It is the result of a collaboration between CSIC, University of Liverpool, and the Polish Academy of Science. It presents the first multi-meridian corneal imaging device, based on a swept-source optical coherence tomography system with high transverse scanning frame rates, to measure a promising early keratoconus biomarker based on air-puff-induced deformation asymmetry. The system will serve both as the basis for determining the minimum viable specifications for a keratoconus screening device based on a deformation asymmetry biomarker, and as a platform to estimate patient-specific corneal biomechanical properties, that can be fed in corneal surgery planning simulators. Currently the system is employed in a pilot clinical study with Keratoconus and Lasik-candidate subjects in collaboration with Fernandez Vega Ophthalmological Institute.
Full reference: Andrea Curatolo, Judith S. Birkenfeld, Eduardo Martinez-Enriquez, James A. Germann, Geethika Muralidharan, Jesús Palací, Daniel Pascual, Ashkan Eliasy, Ahmed Abass, Jędrzej Solarski, Karol Karnowski, Maciej Wojtkowski, Ahmed Elsheikh, and Susana Marcos, "Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities," Biomed. Opt. Express 11, 6337-6355 (2020)
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